MyHep All (Sofosbuvir/Velpatasvir) is combination of two antiviral substances used in the treatment of hepatitis C. Sofosbuvir is a pangenotypic inhibitor of the RNA-dependent RNA polymerase NS5B of the hepatitis C virus (HCV) required for viral replication. Velpatasvir also has antiviral activity against the hepatitis C virus. It affects the NS5A protein, and thus helps reduce viral load.