Glucophage Metformin Hydrochloride) is a hypoglycemic drug used in patients with type 2 diabetes mellitus. Glucophage Metformin Hydrochloride) improves the status of patients with type 2 diabetes by reducing glucose, glycosylated hemoglobin, and increasing glucose tolerance. Glucophage 1000mg (Metformin Hydrochloride) also reduces absorption of glucose in the intestine and improves the sensitivity of peripheral tissues to insulin, which improves the absorption of glucose and its metabolism.