Genkeran (Chlorambucil) is a cytostatic, antitumor drug. It interacts with nucleophilic centers of DNA and RNA (especially guanidine bases), forming strong covalent bonds with them, which disrupts DNA replication and damages RNA. Genkeran (Chlorambucil) is used to treat lymphogranulomatosis, non-Hodgkin`s lymphoma, chronic lymphocytic leukemia, Waldenstrom macroglobulinemia.
