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Genox (Tamoxifen Citrate) is an antiestrogen which can treat various forms of breast cancer by competing with estrogen for the binding receptors in the breast tissue. Breast cancer cells need estrogen in order to proliferate and spread. However, because this medicine is able to attach to the estrogen receptor in the cancer cells, it can block estrogen from binding to these cells. The cancer cells are dependent on estrogen for their growth, and without it, they are prevented from growing. This helps to treat the cancer.
In some cases, it may be used together with radiation therapy, surgical procedures or chemotherapy to treat breast cancer in certain categories of patients, and it may even lower the risk of contralateral breast cancer. Female patients who have undergone treatment for noninvasive cancer (ductal carcinoma in situ or DCIS) are sometimes treated with this drug, so as to help lower the risk of invasive breast cancer. Metastatic breast cancer (in men or women) has also been treated with it.
Women who are considered to be in the high risk category for developing breast cancer are sometimes told to undergo treatment with this medicine to reduce the possibility of developing the condition. Some physicians have also treated patients for Albright`s syndrome with it. Recently, a team of medical researchers conducted a study to determine whether or not it would work for the treatment of gynecomastia in men (a condition which causes enlarged and painful breasts, which is thought to be related to estrogen or testosterone abnormalities).
Genox (Tamoxifen Citrate) is available as 10mg and 20mg strength tablets for oral administration. If used as an adjuvant therapy for node-positive breast cancer in women who have undergone surgery or radiation therapy, there is a possibility that the physician will direct the patient to take 10mg by mouth, 2 to 3 times per day.
Patients treating DCIS or those who have been instructed to use it so as to reduce the risk of breast cancer may be directed by their physician to administer 20mg per day, with treatment continuing for 5 years. McCune Albright syndrome and other conditions may require a different dosage schedule and patients must fully comply with the dosage regimen provided to them by the physician in charge of treatment.
Patients undergoing medical therapy with Genox (Tamoxifen Citrate) should ask their physician about the possible side effects which may occur throughout the course of treatment. Some of these can include:
Visit your physician regularly to report any side effects which you notice. You will be required to attend the hospital or consult your physician immediately if you notice a lump on the breast which was not there before, problems related to eyesight, fever or any other severe reactions and side effects.
Patients taking Genox (Tamoxifen Citrate) may be required by their physician to have regular mammograms and breast checks, as breast cancer can sometimes develop in patients taking this medicine.
Should you notice an abnormal vaginal discharge, see you physician straight away. This could be a sign of cancer of the uterus. Also, serious blood clots have been associated with this medicine in some cases. Talk about the risks of treatment with your physician before beginning treatment.